Alternative titles; symbolsPTPRF-INTERACTING PROTEIN ALPHA-4LIPRIN-ALPHA-4HGNC Approved Gene Symbol: PPFIA4Cytogenetic location: 1q32.1 Genomic coordinates (...
Alternative titles; symbols
HGNC Approved Gene Symbol: PPFIA4
Cytogenetic location: 1q32.1 Genomic coordinates (GRCh38): 1:203,026,490-203,078,735 (from NCBI)
PPFIA4, or liprin-alpha-4, belongs to the liprin-alpha gene family. See liprin-alpha-1 (LIP1, or PPFIA1; 611054) for background on liprins.
▼ Cloning and Expression
Serra-Pages et al. (1998) identified a family of genes encoding LIP1-related proteins, or liprins. The sequence of the predicted partial 500-amino acid liprin-alpha-4 protein is 75% identical to that of LIP1. Northern blot analysis revealed that the liprin-alpha-4 gene is expressed as a 7.5-kb mRNA only in heart, brain, and skeletal muscle.